PROscope

PROscope is a non-invasive, objective diagnostic tool for sports-related concussions. Using a novel algorithm with camera-mounted eyeglasses, we can capture and analyze oculomotor and head movement data to identify signs of neurophysiological dysfunction.

Our preliminary data support the tool's ability to detect deficits that are not otherwise available with current testing methods. The project’s long-term goal is to validate these biomarkers, achieve FDA approval, and support widespread clinical adoption across sports medicine, emergency care, military, and other sports settings. A secondary target is the detection of neurodegenerative disease.

Our ongoing validation study involves athletes aged 14–22 and compares biomarker data from our tool with standard clinical assessments. Additionally, we are building a predictive model to monitor recovery by tracking biomarker changes over time, enabling informed return-to-play decisions based on real-time physiological data.

The study is non-invasive. Our enrollment is expanding, and we want to increase our validity through research partners. The test itself is easy to set up with minimal hardware requirements. The total time of testing is 3 minutes. 

This technology has the potential to redefine concussion care by providing clinicians with a scalable, accurate, and accessible diagnostic solution. Further potential exists in defining a cutoff score for neurodegenerative disease, and we are looking for partners in neurology to help further that research.

PROscope Clinical Benefits

Clinicians and athletic trainers' utilization of an objective concussion biomarker test to: 

1. Enhance diagnostic certainty
2. Improve the quality of care
3. Streamline patient management
4. Ensure athletes are properly triaged

Target Performance Requirements 

• Quantitative, non-invasive biomarker indicative of concussion and neurodegenerative disease
• Time-efficient and non-effort-dependent objective concussion diagnostic results
• Tracking neurological recovery and disease state over time means efficient treatment planning and safe return to play
• Deep Neural Network Artificial Intelligence supported, which provides a better understanding of risk factors for concussion, CTE, SIS